John-William Sidhom | John-William Sidhom, M.D.,Ph.D.

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Immune checkpoint therapy responders display early clonal expansion of tumor infiltrating lymphocytes
When We Became Doctors
Miracles in Medicine
Comparing anti-tumor and anti-self immunity in a patient with melanoma receiving immune checkpoint blockade
Good For You
Multiple-instance learning of somatic mutations for the classification of tumour type and the prediction of microsatellite status
Growth over Outcomes
Consistency // Flexibility
Probabilistic mixture models improve calibration of panel-derived tumor mutational burden in the context of both tumor-normal and tumor-only sequencing
My Identity Crisis
Deep learning reveals predictive sequence concepts within immune repertoires to immunotherapy
The Null Hypothesis
Deep learning reveals predictive sequence concepts within immune repertoires to immunotherapy
Deep learning identifies antigenic determinants of severe SARS-CoV-2 infection within T-cell repertoires
Anti-PD-1 elicits regression of undifferentiated pleomorphic sarcomas with UV-mutation signatures
DeepAPL
Deep learning for diagnosis of acute promyelocytic leukemia via recognition of genomically imprinted morphologic features
Goodhart's Law
DeepTCR is a deep learning framework for revealing sequence concepts within T-cell repertoires
The Physician's Garage (TPG)
ExCYT
Deep Learning for Distinguishing Morphological Features of Acute Promyelocytic Leukemia
Integrative Tumor and Immune Cell Multi-omic Analyses Predict Response to Immune Checkpoint Blockade in Melanoma
Multiple genetic programs contribute to CD4 T cell memory differentiation and longevity by maintaining T cell quiescence
I See Fire (Duo) - Ed Sheeran
Aggregation Tool for Genomic Concepts (ATGC): A deep learning framework for sparse genomic measures and its application to tumor mutational burden
Analysis of SARS-CoV-2 specific T-cell receptors in ImmuneCode reveals cross-reactivity to immunodominant Influenza M1 epitope
Compartmental Analysis of T-cell Clonal Dynamics as a Function of Pathologic Response to Neoadjuvant PD-1 Blockade in Resectable Non–Small Cell Lung Cancer
High-Dimensional Cytometry (ExCYT) and Mass Spectrometry of myeloid infiltrate in clinically localized clear cell Renal Cell Carcinoma identifies novel potential myeloid targets for immunotherapy
DeepTCR: A Deep Learning Framework for Revealing Structural Concepts within TCR Repertoire
A CD40 Agonist and PD-1 Antagonist Antibody Reprogram the Microenvironment of Nonimmunogenic Tumors to Allow T-cell–Mediated Anticancer Activity
Persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1
ExCYT: A Graphical User Interface for Streamlining Analysis of High-Dimensional Cytometry Data
DeepTCR: A Deep Learning Framework for Revealing Structural Concepts within TCR Repertoire
DeepTCR: a deep learning framework for revealing structural concepts within TCR Repertoire
Deep Learning of the Immune Synapse
The Mutation-Associated Neoantigen Functional Expansion of Specific T Cells (MANAFEST) Assay: A Sensitive Platform for Monitoring Antitumor Immunity
AI-MHC: an allele-integrated deep learning framework for improving Class I & Class II HLA-binding predictions
Convolving Pre-Trained Convolutional Neural Networks at Various Magnifications to Extract Diagnostic Features for Digital Pathology
Neoadjuvant PD-1 Blockade in Resectable Lung Cancer
ImmunoMap: A Bioinformatics Tool for T-cell Repertoire Analysis
Radiotherapy and CTLA-4 Blockade Shape the TCR Repertoire of Tumor-Infiltrating T Cells
ICIAR 2018
Tumor and Microenvironment Evolution during Immunotherapy with Nivolumab
Cryotherapy device and method for the treatment of cervical precancerous lesions
Dual Targeting Nanoparticle Stimulates the Immune System To Inhibit Tumor Growth
ImmunoMap: A Novel Bioinformatics Tool for Immune Cell Repertoire Analysis
ImmunoMap
ImmunoMap: A Novel Bioinformatics Tool for Immune Cell Repertoire Analysis
CryoPop
OrthoPure
GastroAnalytics
Dynamics of Electrically Coupled Harmonic Oscillators
Magnetic Ventures
Device and method for force management within a joint