John-William Sidhom

John-William Sidhom

Internal Medicine Resident, PGY-3

Mount Sinai Hospital

Icahn School of Medicine


Thanks for stopping by and checking out my personal page. I am an Internal Medicine resident physician at the Mount Sinai Hospital in the Icahn School of Medicine, and incoming heme/onc fellow at Weill Cornell Medicine. Prior to joining the Mount Sinai Hospital internal medicine residency program, I completed an MD/PhD from the Johns Hopkins University within the School of Medicine and Whiting School of Engineering.

Doctoral Work

My doctoral work (Thesis Advisor: Drew M. Pardoll, MD.,PhD., Co-Mentor: Alexander S. Baras, MD,.PhD.) was at the intersection of artificial intelligence, machine learning, and cancer immunogenomics where I worked on several projects applying and/or developing novel algorithmic approaches to yield insights into the interaction of cancer and the immune system.

Pre-Doctoral & Master’s Work

Prior to matriculating into the MD/PhD program at Johns Hopkins, I completed a Bachelor of Science in Engineering (BSE) in Biomedical Engineering with a minor in mathematics and certificate of entrepreneurship at the University of Michigan in 2011. Following my undergraduate degree, I went on to complete a Master’s of Science & Engineering in Biomedical Engineering within the Center for Bioengineering Innovation and Design at Johns Hopkins. During this time (read about my experience in CBID here), I developed an interest and focus in medical device design, applying methods in computational mechanics to invent devices such as the CryoPop, a low-cost cryotherapy unit that utilizes readily available carbon dioxide tanks for the treatment of cervical cancer. The CryoPop has been issued a patent from the USPTO, completed its first clinical trial (NCT02367625), is currently enrolling in its second one (NCT04154644) to demonstrate efficacy, and is commercially available for clinical use through Pregna International Ltd.

Medical Mission

I also serve on the board of the student chapter of the Coptic Medical Association of North America (CMANA) as its current treasurer. As part of the student chapter, I have helped organized our annual conferences and local events that allow medical trainees at all stages to experience medical missions through the mother organization. Our student chapter also organizes opportunities for networking including online talks/forums, an annual gala, and quarterly newsletter.

Hobbies & Interests

When I am not coding away or in the hospital, I enjoy staying physically active (CrossFit, Olympic weightlifting, skiing), playing and producing music (singing, piano, guitar), and amateur photography. Otherwise, I enjoy visiting new cities, eating good food, and having a fun time with friends, family, & my dog Leo.

Contact Me!

I hope this page provides insight into the work I have done and areas of research I hope to continue to pursue in my future career as well as my own personal interests! Feel free to contact me and reach out with any questions or research collaboration opportunities!


  • Cancer Immunology
  • Artificial Intelligence
  • Deep Learning
  • Immunogenomics
  • Internal Medicine
  • Medical Oncology


  • Doctorate of Medicine, 2021

    Johns Hopkins University School of Medicine

  • Doctorate of Philosophy in Biomedical Engineering, 2021

    Johns Hopkins University Whiting School of Engineering

  • Master's of Science & Engineering in Biomedical Engineering, 2012

    Johns Hopkins University Whiting School of Engineering

  • Bachelor of Science in Engineering in Biomedical Engineering, 2011

    University of Michigan

  • Deep Learning Nanodegree

    Udacity School of AI



Resident Physician - Internal Medicine

Icahn School of Medicine at the Mount Sinai Hospital

Jul 2021 – Present New York, NY

Visiting Scholar

Microsoft Research

Feb 2019 – Aug 2019 Cambridge, MA

Board Member & Treasurer

CMANA Student Chapter

Jan 2016 – Present Manlius,NY

MD/PhD Student

Johns Hopkins University

Aug 2012 – May 2021 Baltimore, MD
  • Doctorate of Medicine
  • Doctorate of Philosophy in Biomedical Engineering

Master’s Student

Johns Hopkins University

Jun 2011 – May 2012 Baltimore, MD
  • M.S.E. in Biomedical Engineering
  • Center for Bioengineering Innovation and Design
    Medtronic Fellow - Graduate Fellowship

Undergraduate Student

University of Michigan

Sep 2007 – May 2011 Ann Arbor, MI
  • B.S.E. in Biomedical Engineering
  • Minor in Mathematics
  • Certificate of Entrepreneurship


See more…




Deep learning for diagnosis of Acute Promyelocytic Leukemia via recognition of genomically imprinted morphologic features


A deep learning framework for revealing sequence concepts within T-cell repertoires

The Physician’s Garage (TPG)

Synthesizing the worlds of engineering and clinical medicine


A Graphical User Interface for Streamlining Analysis of High-Dimensional Cytometry Data

ICIAR 2018

My first foray into deep learning


A Structural Bioinformatics Tool for T-cell Repertoire Analysis


Enabling Affordable Prevention of Cervical Cancer in the Developing World


Filtering immunogenic wear debris to extend the lifetime of artificial joint replacement


Digital manometry for diagnosis of dyssynergic defecation

Dynamics of Electrically Coupled Harmonic Oscillators

Thesis from course in nonlinear dynamics and chaos theory

Magnetic Ventures

A dynamic unloading technology to extend the lifetime of artificial joint replacement


Recent Publications

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Young Investigator Award

Paul & Daisy Soros Fellowship Finalist

Semi-finalist in Dell Social Innovation Challenge – CryoPop

Women’s Health and Wellness Innovations Award - CryoPop

1st Place in Social Enterprises - CryoPop

Center for Bioengineering Innovation and Design - Medtronic Fellow

Michigan Daily’s Student of the Year

NCIIA E-Team Grant Recipient – Magnetic Ventures

College of Engineering Dean’s List and University Honors